People

Current Lab Members

Principal Investigator (P.I.)

 
  Steven C. George, MD, PhD, Professor, Biomedical Engineering, scgeorge@ucdavis.edu. Project(s): lead the lab!
 

 

Professional Staff and Project Scientists

 
  Dr. Bhupinder Shergill,  Project Scientist and Laboratory Manager (2017-), bdshergill@gmail.com. Project(s): Oxygen tension measurements in pancreatic microenvironment; Coordinates and organizes lab activities including training, equipment maintenance, safety, and purchasing; endothelial cell sourcing, lentiviral transduction.
Venktesh Shirure (2013-), Project Scientist, vsshirure@gmail.com​. Project(s): models of the tumor microenvironment; tumor angiogenesis; mechanisms of tumor metastasis; microfabrication.
Sergey Yechikov (2017-), Project Scientist, s.yechikov@gmail.com​. Project(s): 3D in vitro models of atrial conduction using iPS derived cardiomyocytes.


 

Post-Doctoral Scholars

 
  Drew Elizabeth Glaser (2014-), dglaser@wustl.edu. Project(s): tumor progression and metastasis; in vitro modeling of bone marrow and cancer dormancy.
  Nuala Del Piccolo (2017-), ndelpiccolo@ucdavis.edu​. Project(s): lymphocyte isolation from the tumor microenvironment and peripheral blood for immunotherapy applications.
Sherri Biendarra-Tiegs (2019-), smbiendarratiegs@ucdavis.edu.  Project(s): 3D in vitro model of atrial conduction
   
  

Doctoral Graduate Students

 
  Matthew Curtis (2016-), mbcurtis@ucdavis.edu​. Project(s): “Breast cancer-on-a-chip” to enhance patient-specific treatment; Stem-derived vascular networks for autologous microphysiological systems.
Zachary Rollins (2019 -), zarollins@ucdavis.edu. Project(s): still exploring.
  Pete Sariano (2018-), (NSF Graduate Research Fellow), pasariano@ucdavis.edu. Project(s): immunoengineering.
  

Undergraduate Students

 

  Aravind Anand (2018-), (mentor:  Drew),  Project(s): tumor progression and metastasis; in vitro modeling of bone marrow and cancer dormancy.
  Alyssa Deely (2017-), (mentor:  Drew),  Project(s): tumor progression and metastasis; in vitro modeling of bone marrow and cancer dormancy.
  Laura Houshand (2017-), (mentor:  Sergey),  Project(s): 3D in vitro models of atrial conduction using iPS derived cardiomyocytes.
Sagie Mofsowitz (2018-), (mentor:  Sergey),  Project(s): 3D in vitro models of atrial conduction using iPS derived cardiomyocytes.

 

Eshani Moghe(2019-), (mentor:  Venktesh),  Project(s):models of the tumor microenvironment; tumor angiogenesis; mechanisms of tumor metastasis; microfabrication. 
  Recruiting new undergraduates researchers – Fall 2019
 
 

Alumni

  

Professional Staff 

 Cristi King,  Laboratory Manager (2014-7), crking@wustl.edu. Project(s): Coordinates and organizes lab activities including training, equipment maintenance, safety, and purchasing; endothelial cell sourcing, lentiviral transduction.
Dorit Daphna-Iken, PhD, Research Scientist (2014-2015), dorit@wustl.edu. Project(s): microphysiological systems; tissue engineering​.
Anna Aledia, Staff Research Associate (2004-2014), aaledia@uci.edu. Project(s): human subjects research, IOS, exhaled nitric oxide; IRB and IACUC compliance; small animal experiments.
Linda McCarthy, Lab Assistant/Coordinator (2009-2013), mccarthl@uci.edu. Project(s): Coordinates and organizes lab activities including training, equipment maintenance, and purchasing; stem cell culture.
 Jennifer NguyenAssistant Specialist (2009-2011), jennifer.tl.nguyen@gmail.com. Project(s): exhaled nitric oxide in children; mobile asthma van in collaboration with Children’s Hospital of Orange County.
 Ahramahzd TatavoosianJunior Specialist (2009-2011), atatavoo@gmail.com. Project(s): exhaled nitric oxide in children; mobile asthma van in collaboration with Children’s Hospital of Orange County.
 

Post-doctoral Researchers​ 

Vasudha Murlidhar (2017-), vmurlidhar@ucdavis.edu​. Project(s): microfabrication; 3D in vitro model of atrial conduction; tumor cell migration.​
Kuo-Chan “KC” Weng (2015-17), kuochan.weng@wustl.edu. Project(s): microphysiological systems to model cardiac development.
Mary Kathyrn (“MK”) Sewell-Loftin (2014-17), m.k.sewell-loftin@wustl.edu. Project(s): biomechanical role of cancer-associated fibroblasts (CAFs) in tumor progression.
Kristen Seiler (2016-), seilerk@wudosis.wustl.edu​. General Surgery Resident. Project(s): intestinal angiogenesis and regenerative mechanisms.​
Priscilla Hwang (2015-17), priscillahwang@wustl.edu​. Project(s): tumor progression and metastasis; micryphysiological systems; cell-cell interactions in the bone marrow.
Mahama Aziz Traore (2014-2016), mahamatraore@wustl.edu. Project(s): tissue engineering arterioles; microphysiological system model of the pancreatic islet.​
Christopher Heylman (2013-2014), (Hewitt Foundation Fellow) cheylman@gmail.com. Project(s): 3D models of human cardiac muscle; human induced pluripotent stem cells.Current Position: Post-doctoral researcher in the lab of Professor Enrico Gratton, UCI.
 Monica Moya, PhD (2009-2014), (NIH F32 Postdoctoral Fellowship) monicamoya@gmail.com. Current Position: Scientist, Lawrence Livermore National Laboratory. Project(s): High throughput platform of 3-D human microtissues characterized by perfusion with human capillaries.
 Jian Zhou, PhD (2010-2013), jianzhou.bioe@gmail.com. Current Position: Associate Professor, Fudan University, China. Project(s): airway epithelial cell injury; smooth muscle contraction; multiscale biomechanics; linking optical, biological, and mechanical properties of airway mucosa.
 Stephen P. Arold, PhD (2006-2008), stephen_arold@hotmail.com Current Position: Senior Scientist, Pulmatrix Inc, Lexington, MA. Project(s): mechanical perturbation and signal transduction in airway epithelial cells; mechanisms of subepithelial fibrosis
 Hye-Won (Jenny) Shin, PhD (2001-2008), hyewons@uci.edu. Current Position: Project Scientist in the Department of Pediatrics, UCI). Project(s): endogenous exchange of nitric oxide in the lungs. NO-GSNO metabolism
 Vinod A. Suresh, PhD (2004-2007), vinod.suresh@gmail.com Current Position: Assistant Professor at the University of Auckland. Project(s): exhaled nitric oxide, NO production and release in lung airway epithelial cells, microfabricated devices
 Peter Condorelli, PhD (2001-2006), Peter.Condorelli@fluor.com (currently a Senior Process Engineer at Fluor Daniel).
Project(s): transport phenomena in pulmonary airways; dynamics of nitric oxide donor transport; heat and mass transfer coefficients.
 H. Garrett Thompson, PhD (2003-2005), GarrettThompson@scuhs.edu. Current Position: Associate Professor in the Department of Basic Sciences, Southern California University of Health Sciences, Los Angeles College of Chiropractic)
Project(s): lung tissue remodeling, multiphoton microscopy, angiogenesis in the airways
 Wanda Walzcak, Ph.D. (2003), wwalczak@laser.bli.uci.edu. Project(s): lung tissue remodeling, multiphoton microscopy (with Dr. Bruce Tromberg).
 Cheryl Miller, Ph.D. (2000-2002), cmille42@slu.edu (currently an Assistant Professor of Biomedical Engineering at St. Louis University) Project(s): tissue engineered airway and implantable prevascularized tissue.
 Sanxiu Lu, Ph.D. (2001). Project(s): biodegradable microspheres to release nitric oxide.
 Yeo Hong Yoon, Ph.D. (1998-1999). Project(s): heat transfer in the lungs; non-invasive measurement of cardiac output.
 

Doctoral Students​

Sandra Lam (2013-18), (CARE trainee, NHLBI T32, NSF Graduate Research Fellow), sandra.lam@wustl.edu. Project(s): measuring and controlling oxygen tension in the in vitro tissue microenvironment; microfabrication; microfluidic devices; microphysiological systems.
Yosuke Kurokawa (2013-17), (AHA predoctoral fellowship)  kurokawa.yosuke@gmail.com. Project(s): cardiac tissue modeling in 3D microphysiological systems.
Kyaw Thu Minn (2015-17), kminn@wustl.edu​. Project(s): gastrulation and cardiac development; microphysiological systems; (co-advised with Professor Lila Solnica-Krezel).
Luis Alonzo (2010-2015), (NIH F31 Fellowship) lalonzo@uci.edu. Project(s): High throughput platform of 3-D human microtissues characterized by perfusion with human capillaries; cancer microenvironment.
Lei Tian (2009-2015), (CIRM Graduate Training Fellowship) tianl@uci.edu. Project(s): prevascularization of implantable tissues with a particular emphasis on developing thick tissues (> 1cm).
David Tran (2010-2015), david.tran@uci.edu. IFER Graduate Research Fellowship. Project(s): cardiomyocyte differentiation from embryonic and induced pluripotent stem cells; mechanical stimulation of stem cells.​
Ehsan Seema (2010-2014), ehsan.seema@gmail.com. Current Position: Associate Program Manager  at Genentech. (Public Impact Fellowship 2013; NSF EAPSI Award Summer 2013 Osaka, Japan). Project(s): intermittent hypoxia; 3-D engineered tumor tissues; angiogenesis. 
Nick Merna (2010-2014), nmerna@uci.edu. Current Position: postdoctoral researcher at Hofstra University. Project(s): decelluarizing cardiac tissue; 3-D engineering tissues; multiphoton img.
 Sean White (2009-2013), (NSF Graduate Fellowship) opticscat@gmail.com. Current Position: postdoctoral research with Profs. Botvinick and Choi. Project(s): wide field functional imaging of blood flow in prevascularized tissues following implantation, including laser speckle and spatially modulated imaging. (Co-advised with Bernard Choi)
 Claire Robertson (2009-2013), (NSF Graduate Fellowship; ARCS Scholar) clairejanerobertson@gmail.com. Current Position: Postdoctoral Researcher with Mina Bissel, Lawrence Berkeley Labs. Project(s): optical tools to investigate biomechanics in vivo and in vitro. Applications include airway and artery remodeling, cardiomyocyte contraction frequency, variability and synchronicity when in co-culture with other cell types.
 Vivien Shi (2008-2012), vivien.shi@uci.edu. Current Position: seeking employment. Project(s): proximal and distal airway inflammation and caliber in children with asthma; impulse oscillometry; exhaled nitric oxide.
 Jingjing Jiang (2006-2011), jiangjingjing@gmail.com. Current position: Postdoctoral Research with Professor Gerry Boss, BiomedicalSciences, UC-San Diego. Project(s): nitric oxide metabolism and release in airway epithelial cells.
 Xiaofang Chen (2005-2009), xchen1@uci.edu. Current position: Assistant Professor, School of Biomedical Engineering, Beijing University of Aeronatucis and Astronautics. Formerly Postdoctoral Research with Professor Amy Herr, Dept of Bioengineering, UC-Berkeley . (“Best Poster” award, HSSOE Symposium, 2007) Project(s): prevascularization of implantable tissues with a particular emphasis on developing fibroblast-encapsulated fibrin beads.
 David Shelley (2005-2009), mr.dave.shelley@gmail.com. Current position: Engineering Scientist, L-3 Communications, Del Mar, CA . Project(s): dynamics of exhaled nitric oxide exchange, glutaminase activity, non-enzymatic production of NO, integrative modeling from the cellular to whole organ levels.
 Chris Raub (2005-2009), craub@bioeng.ucsd.edu. Current position: post-doctoral researcher with Professor Robert Sah, UCSD. Project(s): mechanism of subepithelial fibrosis in asthma with a focus on correlating changes in the optical properties (second harmonic generation) with mechanical properties of the extracellular matrix.
 James “Lee” Puckett (2007-2009), jpuckett@uci.edu. Current position: Medical Resident, Emergency Medicine, UCI. Project(s): exhaled nitric oxide in children and adults; partioning exhaled NO into alveolar and airway components; clinical translation of exhaled NO models.
 Nikita Malavia (2004-2008), nkmalavia@gmail.com. Current position: Product Development Engineer, SKS Ocular, LLC; formerly post-doctoral researcher, Harvard University and MIT with Robert Langer. Project(s): lung tissue remodeling, subepithelial fibrosis in asthma, airway smooth muscle cell culture and remodeling, nitric oxide metabolism.
 Cyrus Ghajar (2004-2008), cghajar@fhcrc.org. Co-advisor with Dr. Andrew Putnam. Current position: Research Scientist, Fred Hutchinson Cancer Research Center, Seattle, WA. Project(s): prevascularization of implantable tissues, impact of mechanical properties on in vitro vessel formation.
 Craig Griffith (2002-2008), craig_griffith@bd.com OR griffithck@gmail.com. Current position: Key Account Manager, BD Bioscience; formerly post-doctoral resarcher at Rutgers University with Professor Prabhas Moghe. (“Best Poster” award, 2004 UC Systemwide Bioengineering Symposium). Project(s): design of an implantable pre-vascularized tissue construct
 Hoon Sung Jeh (1998-2002), hsjeh@lgls.co.kr. Current Position: Principal Scientist and Research Fellow at LG Life Sciences in Korea. Project(s): nitric oxide donor transport in the alveolar region of the lungs; biodegradable nitric oxide donors.
 Wei-yang Wu (1996-2001), wwu@sovpharm.com. Current Position: Analytical Scientist, Sovereign Pharmaceuticals, Fort Worth, TX). Project(s): diffusion and reaction of peptides and small molecules in the respiratory mucosa; tissue engineering lung mucosa using collagen gels
 Hye-won (Jenny) Shin (1998-2001), hyewons@uci.edu Current Position: Project Scientist in the Department of Pediatrics at UCI. Project(s): endogenous exchange of nitric oxide in the lungs.
 Peter Condorelli (1996-2001), pcondore@uci.edu (currently a Senior Process Engineer at Fluor Daniel)
Project(s): transport phenomena in pulmonary airways; dynamics of nitric oxide donor transport; heat and mass transfer coefficients.
 Angelie Agarwal (1997-2001), angelie.agarwal@gmail.com . Current Position: Senior Marketing Manager for GlobalLogic in San Francisco, CA). Project(s): engineered lung tissue; extracellular matrix protein expression and remodeling in collagen gels
 Soonjo Kwon (1995-2000), skwon@cc.usu.edu Current Position: Assistant Professor in Biological Engineering at Utah State University). Project(s): mechanism of synergy for cytokine-induced NO production in cultured lung cells.
Nikoloas M. Tsoukias, (1995-1999) Current Position: Associate Professor in the Department of Biomedical Engineering at Florida International University). Project(s): transport phenomena in pulmonary airways; dynamics of nitric oxide donor transport.
 

Masters Students

 Kareena Tauro (2010-11), ktauro@uci.edu. Project(s): creating a thick in vitro prevarized tissues.
 Justin Mih, 2003-2006
 Yuan Su, 1998-9 
 Benjamin Wong, 1997-8 (now at Western Digital) 
 Thien Bui, 1996-7 (started own company, Ndex International) 

 

Undergraduate Researchers

Vishal Manickam (2017-19), (mentor:  Venktesh),  Project(s):models of the tumor microenvironment; tumor angiogenesis; mechanisms of tumor metastasis; microfabrication. 
Justin Diec (2017-19), (mentor:  Venktesh),  Project(s):models of the tumor microenvironment; tumor angiogenesis; mechanisms of tumor metastasis; microfabrication.
Lipika Giri (2017-), (mentor:  Matt),  Project(s):”Breast cancer-on-a-chip” to enhance patient-specific treatment; Stem-derived vascular networks for autologous microphysiological systems.
Andrea E Garcia Ruvalcaba (2017-), (mentor:  Nuala),  Project(s): lymphocyte isolation from the tumor microenvironment and peripheral blood for immunotherapy applications.
Carly Krull (2015-2016), krull.carly@wustl.edu​
Project(s): tumor metastasis.  (Mentor: Drew)
Jessica Lin (2015-2016), linjessica@wustl.edu
Project(s):  vascularized cardiac microphysiological systems derived from iPS cells. (Mentor: Aziz)​​
Benjamin Aunins (2015-2016) baunins@wustl.edu​
Project(s): tumor progression and metastasis; breast cancer and the bone marrow; microphysiological systems. (Mentor: Priscilla)​ 
​​​Elizabeth “Lizzy” Crist (2015-), lizzy.crist@wustl.edu
Project(s): Studying the role of ECM composition on CAF-mediated angiogenesis. (Mentor: MK)
Brianna Hajek (2016-), b.hajek@wustl.edu
Project(s): microphysiological systems to model cardiac development. (Mentor: KC)
Brian “Taylor” Hughes (2015-), taylorhughes@wustl.edu
Project(s): Characterizing CAF biomechanical behavior in 3D tissue models.  (Mentor: MK)
Rachel Jacobsohn (2016-), rjacobsohn@wustl.edu
Project(s): tumor progression and metastasis; micryphysiological systems; cell-cell interactions in the bone marrow. (Mentor: Priscilla)
Sofia Joison (2015-), sofiamjoison@wustl.edu
Project(s): Studying the role of ECM composition on CAF-mediated angiogenesis. (Mentor: MK)
Andrew Lezia (2014-), alezia@wustl.edu
Project(s): Angiogenesis in the tumor microenvironment. (Mentor: Venktesh)
Hongyi “Richard” Li (2014-), li.richard@wustl.edu
Project(s): vascularized microphysiological systems. (Mentor: Aziz)​
Rohan Khopkar (2015-), khopkar.rohan@wustl.edu
Project(s):  vascularized cardiac microphysiological systems derived from iPS cells. (Mentor: Venktesh)
Jack Paladin (2016-), jackpaladin@wustl.edu​
Project(s): microphysiological systems to model cardiac development.​ (Mentor: KC)
Michael Shang (2014-), m.shang@go.wustl.edu
Project(s): vascularized cardiac microphysiological systems derived from iPS cells. (Mentor: Yosuke)
Alan Soetikno (2014-), alan.soetikno@wustl.edu
Project(s): Microfabrication of microfluidic devices to control oxygen tension. (Mentor: Sandra)
Arnold Tao (2014-), arnoldtao@wustl.edu
Project(s): Angiogenesis in the tumor microenvironment. (Mentor: Venktesh)
Rose Yin (2015-), roseyin@wustl.edu
Project(s): vascularized cardiac microphysiological systems derived from iPS cells. (Mentor: Yosuke)
  Matt Curtis (2012-2014), mbcurtis@uci.edu
Project(s): Intermittent hypoxia and 3-D angiogenesis. (Mentor: Seema Ehsan)
 Vinson Tran (2013-14), vinsont@uci.edu
Project(s): models of the tumor microenvironment; tumor angiogenesis; mechanisms of tumor metastasis; microfabrication. (Mentor: Venktesh Shirure)Miranda Ramirez (2012-13), Mira2ramirez@gmail.com
Project(s): Cardiomyocyte differentitation of embryonic and induced pluripotent stem cells using mechanical stimulation. (Mentor: David Tran)
 Jessica Motherwell (2012-14), jmotherw@uci.edu
Project(s): prevascularizing implantable 3-D tissues. (Mentor: Lei Tian)
 Pearl Law (2013-14), pllaw@uci.edu
Project(s): creating vascularized cardiomyocyte spheroids from induced pluripotent cells. (Mentor: David Tran)
 Lisa Luevano (2013-14), luevanol@uci.edu
Project(s): developing a training algorithm to characterize vascular networks from brightfield images. (Mentor: Luis Alonzo)
 Amin Gosla (2013-14), agosla@uci.edu
Project(s): iPS-derived cardiomyocytes. (Mentor: Chris Heylman)
 Kelsey Fung (2013-14), kmfung@uci.edu
Project(s): decelluarizing cardiac tissue; 3-D engineering tissues; multiphoton imaging. (Mentor: Nick Merna)
 Nicholas Flohn (2013-14), nflohn@uci.edu
Project(s): Electrical pacing of cardiomyocytes derived induced pluripotent stem cells. (Mentor: David Tran)
 Kevin Cho (2012-14), choks@uci.edu
Project(s): prevascularizing implantable 3-D tissues. (Mentor: Lei Tian)
 Zachary (Zach) Campagna (2012-14), zcampagn@uci.edu
Project(s): in vitro modeling of the tumor microenvironment. (Mentor: Luis and Monica)
 Alexandra (Ali) Crampton (2011-13), acrampto@uci.edu
Project(s): 3-D tumor microenvironment (Mentor: Luis Alonzo)
 Anh La (2011-13), laat@uci.edu
Project(s): decelluarizing cardiac tissue. (Mentor: Nick Merna)
 Nicole Mendoza (2011-13), nlmendoz@uci.edu
Project(s): intermitten hypoxia and vasculogenesis (Mentor: Seema Ehsan)
 Ken Ikemura (2009-12), kikemura@uci.edu
Project(s): linking optics and mechanics in engineered tissues. (Mentor: Claire Robertson)
 Sourish Bandyopadhyay (2009-12), bandyopa@uci.edu
Project(s): prevascularized implantable tissues. (Mentor: Lei Tian)
 Emerald Chun (2009-12), eachun@uci.edu
Project(s): linking optics and mechanics in engineered tissues. (Mentor: Claire Robertson)
 Katie Mo (2009-12), kmo@uci.edu
Project(s): prevascularized implantable tissues. (Mentor: Lei Tian)
 Shruthi Murali (2010-12), smurali@uci.edu
Project(s): assessing lung function in asthmatic children using the impulse oscillometry system (IOS). (Mentor: Vivien Shi)
 Noemi Perlas (2010-12), nperlas@uci.edu
Project(s): elastography of the rabbit trachea using optical coherence tomography (OCT). (Mentor: Claire Robertson)
 Julie Taylor (2010-12), juliemt@uci.edu
Project(s): 3-D perfused human microtissues. (Mentor: Monica Moya)
 Justin Luo (2010-12), jcluo@uci.edu. Project(s): linking airway wall mechanics with optical images using thin tissue sections. (Mentor: Jian Zhou and Swee Lim)
 Jonathan Hateley (2010-11), hateleyj@uci.edu . Project(s): 3-D perfused human microtissues. (Mentor: Monica Moya)
 Danny Spampinato (2009-11), dspampin@uci.edu . Project(s): prevascularized implantable tissues. (Mentors: Xiaofang Chen and Lei Tian)
 Richard W. Taylor (2008-10), rwtaylor@uci.edu . Project(s): exhaled nitric oxide. (Mentor: Lee Puckett)
 Michael Campos (2007), camposm@uci.edu . Project(s): exhaled nitric oxide. (Mentor: Lee Puckett)
 Edna Santillan (2006-2008), esantill@uci.edu . Project(s): co-culture of normal human bronchial epithelial cells with stromal cells. (Mentor: Nikita Malavia)Amy Shah (2007-2008), ashah120@gmail.com . Project(s): injury response of normal human bronchial epithelial cells. (Mentor: Steve Arold)
 Bao Dinh (2006-2008), btdinh@uci.edu . Project(s): multiphoton microscopy of lung fibroblast embedded collagen and fibrin gels. (Mentor: Chris Raub)
 David Truong (2005-6), dttruong@uci.edu (Winner of HSSOE 2006 Undergraduate Research Award, $1,000). Project(s): vascularized airway mucosa.
 Peter Eskander (2005-6), peskande@uci.edu. Project(s): quantifying vascular networks.
 Danny Chang (2003-2005)
 Adrian Fernandez (2003-2005)
 Brandon Lee (2003-2004)
 Emily Hu (2001-2003)
 Sukon Ip (1998-2000)
 Steven Evans (1999-2000). Project: wound healing and collagen remodeling in the lungs
 Joy Lau (1999-2000). Project: cytokine-induced nitric oxide production in lung cells
 Federico Perez (1998-1999). Project: determining the diffusing capacity of NO in humans
 Sergio Sandoval (1999-2000). Project: wound healing and collagen remodeling in the lungs
 Eric Britten (1998)
 Jacob Fritz (1998)
 Lynher Ramiriz (1998)

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